Fall 2008 6 . 047 / 6 . 878 Lecture 13 Population Genomics II : Pardis Sabeti Scribe : Clara Chan

6 . 047 / 6 . 878 Scribe Notes Lecture 8 – Classification

Again, we come across the distinction between a generative model and a discriminative model. In the context of classification, a generative scheme creates a set of models describing how likely it is for a given feature set to be generated, given the underlying class. As an example, in spam classification, a generative model might model a spam generator by saying that it has a 50% probability of...

6 . 047 / 6 . 878 Lecture 19 : Introduction to Steady State Metabolic

Population Genomics I ( Pardis Sabeti ) Scribed by Arjun

Polymorphisms are DNA variations between different individuals of the same species. There are several types of polymorphisms, including single nucleotide polymorphisms (SNPs), variable number tandem repeats, insertions and deletions, large-scale polymorphisms, and copy number variants. In addition to helping explain the genetic basis of our diversity, understanding polymorphisms is also medical...

6 . 047 / 6 . 878 Fall 2008

Compared to human-engineered artifacts, biological systems are strikingly powerful: they are reliable and flexible, capable of storing information at incredible density, and — most importantly — able to self-replicate. In many ways, biology, when viewed as a technology, is vastly superior to any other. Scientists have been modifying biological systems for many years — both to better understand ...

A malaria fingerprint in the human genome?

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